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I'm currently just taking CBD, but I'm tempted to ask my physician to put me on Adderall. However, after some research, I find that CBD greatly inhibits CYP2D6, an enzyme used to metabolize Adderall. CBD also greatly enhances serotonin, I will answer your question seeing that no one has actually took adderall and smoked before. I took adderall for my ADHD in high school, when I was in college I stopped taking them everyday because I hate how they made me feel(loss of Disocver how to use CBD oil for performance, recovery, and sleep and to basically get all of the health benefits of smoking weed (without smoking It's not like this stuff just popped up like Red Bull energy drinks, ecstasy, Lunesta, or Adderall. My 18 yr old is on that combo at medium high dose and I'd like to wean him off.